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Monday, August 15, 2011

Symptoms of Liver


Symptoms of liver Disease include:
  • nausea, 
  • vomiting, 
  • right upper quadrant abdominal pain, and 
  • jaundice (a yellow discoloration of the skin due to elevated bilirubin concentrations in the bloodstream).
Fatigue, weakness and weight loss may also be occur.
However, since there are a variety of liver diseases, the symptoms tend to be specific for that illness until late-stage liver disease and liver failure occurs.
Examples of liver disease symptoms due to certain conditions or diseases include:
  • A person with gallstones may experience right upper abdominal pain and vomiting after eating a greasy (fatty) meal. If the gallbladder becomes infected, fever may occur.
  • Gilbert's disease have no symptoms.
  • Individuals with cirrhosis will develop progressive symptoms as the liver fails. Some symptoms are directly related to the inability of the liver to metabolize the body's waste products. Others reflect the failure of the liver to manufacture proteins required for body function and may affect blood clotting function, secondary sex characteristics and brain function. Symptoms of cirrhosis of the liver include:
    • easy bruising may occur due to decreased production of clotting factors; 
    • bile salts can deposit in the skin causing itching; 
    • gynecomastia or enlarged breasts in men may occur because of an imbalance in sex hormones; specifically an increase in estradiol; 
    • impotence (erectile dysfunction, ED), poor sex drive and shrinking testicles are due to decrease in function of sex hormones;
    • confusion and lethargy may occur if ammonia levels rise in the blood stream (ammonia is a waste product formed from protein metabolism and requires normal liver cells to remove it); 
    • ascites (fluid accumulation within the abdominal cavity) occurs because of decreased protein production; and
    • muscle wasting may occur because of reduced protein production.
Additionally, there is increased pressure within the cirrhotic liver affecting blood flow through the liver. Increased pressure in the portal vein causes blood flow to the liver to slow and blood vessels to swell. Swollen veins (varices) form around the stomach and esophagus and are at risk for bleeding.

Liver Cancer
  • Abdominal pain or fullness, especially in the right upper abdomen
  • Dark urine
  • Easy bleeding or bruising
  • Enlarged liver
  • Fatigue
  • Fever
  • Generalized muscle weakness and reduced muscle mass
  • Night sweats
  • Pale stool
  • Swelling and fluid collection in the abdomen (ascites)
  • Unexplained weight loss
  • Yellowing of the skin and whites of the eyes (jaundice)

Serious symptoms that might indicate a life-threatening condition

In some cases, liver cancer can be life threatening, especially if internal bleeding or liver failure should occur. Symptoms:
  • Bloody stool (the blood may be red, black, or tarry in texture)
  • Change in level of consciousness or alertness, such as passing out or unresponsiveness
  • Change in mental status or sudden behavior change, such as confusion, delirium, lethargy, hallucinations and delusions
  • Chest pain, chest tightness, chest pressure, palpitations
  • Rapid heart rate (tachycardia)
  • Respiratory or breathing problems, such as shortness of breath, difficulty breathing, labored breathing, wheezing
  • Severe abdominal pain
  • Uncontrolled or heavy bleeding, hemorrhage
  • Vomiting blood

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